A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests.
It appears that the hormone receptor guanylyl cyclase C (GC-C) - a previously identified tumor suppressor that exists in the intestinal tract - plays a key role in strengthening the body's intestinal barrier, which helps separate the gut world from the rest of the body, and possibly keeps cancer at bay. Without the receptor, that barrier weakens.
A team led by Scott Waldman, M.D., Ph.D., chair of the Department of Pharmacology and Experimental Therapeutics at Jefferson and director of the Gastrointestinal Cancer Program at Jefferson's Kimmel Cancer Center, discovered in a pre-clinical study that silencing GC-C in mice compromised the integrity of the intestinal barrier. It allowed inflammation to occur and cancer-causing agents to seep out into the body, damaging DNA and forming cancer outside the intestine, including in the liver, lung and lymph nodes.
For the full article please go here.
Welcome to the AIHCP blog. Members, vistors and friends are welcome to post on our blog. We believe that knowledge and opinion should be shared. We are professional health care organization offering continuing education and certification programs in a wide array of health care speciality practices, including: Grief Counseling, Legal Nurse Consulting, Case Management, Stress Management, Holistic & Integrative Health Care & more. Join the Discussion!
No comments:
Post a Comment