Four gene variants, all members of the glutamate receptor gene family, appear to be involved in vital brain signaling pathways in a sub-set of children with ADHD (attention deficit hyperactivity disorder), researchers from the Center for Applied Genomics at The Children's Hospital of Philadelphia reported in the journal Nature Genetics. The authors add that their findings could help create drugs that target those pathways, offering potential therapies for ADHD patients with those specific gene variants. There are an estimated half-a-million American children with ADHD and these gene variants.
Study leader Hakon Hakonarson, M.D., Ph.D., said:
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